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Gastroenterology

A High-Dose 24-Hour Tranexamic Acid Infusion for the Treatment of Significant Gastrointestinal Bleeding: HALT-IT RCT

Authors: Ian Roberts, Haleema Shakur-Still, Adefemi Afolabi, Adegboyega Akere, Monica Arribas, Emma Austin, Kiran Bal, Nuha Bazeer, Danielle Beaumont, Amy Brenner, Abdelmounem Abdo (Sudan Lead)
Journal: The Lancet / Health Technology Assessment
Date: October 1, 2021
DOI: https://pubmed.ncbi.nlm.nih.gov/32561912/

Abstract

Major international RCT across 15 countries including Sudan (NCGLD as country lead). Concluded tranexamic acid did not reduce mortality and increased thromboembolic risk.

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